botulin botulin /ˈbɒtjʊlɪn/

noun

1. Potent bacterial toxin produced by the bacterium Clostridium botulinum that causes botulism; can be used as a bioweapon  ( botulin , botulinus toxin , botulismotoxin )
   potent bacterial toxin produced by the bacterium Clostridium botulinum that causes botulism; can be used as a bioweapon
   
   

 upgrade upgrade /ˈʌpˈgreɪd/

noun

1. The act of improving something (especially machinery) by raising it to a higher grade (as by adding or replacing components)  ( upgrade )
   the act of improving something (especially machinery) by raising it to a higher grade (as by adding or replacing components)
    The power plant received a new upgrade
   the power plant received a new upgrade
   
2. Hardware that provides better performance than an earlier version did  ( upgrade )
   hardware that provides better performance than an earlier version did
   
3. [ N. American] The property possessed by a slope or surface that rises  ( rising slope , upgrade [ N. American] , rise )
   the property possessed by a slope or surface that rises
   
4. A reservation that is improved  ( upgrade )
   a reservation that is improved
    I got an upgrade to first class when coach class was full
   I got an upgrade to first class when coach class was full
   
5. Software that provides better performance than an earlier version did  ( upgrade )
   software that provides better performance than an earlier version did
   
6. [ N. American] An upward slope or grade (as in a road)  ( acclivity , ascent , climb , raise , rise , upgrade [ N. American] )
   an upward slope or grade (as in a road)
    The car couldn't make it up the rise
   the car couldn't make it up the rise
   
   

verb

1. () Rate higher; raise in value or esteem  ( uprate , upgrade )
   rate higher; raise in value or esteem
   
2. () To improve what was old or outdated  ( upgrade )
   to improve what was old or outdated
    I've upgraded my computer so I can run better software
   I've upgraded my computer so I can run better software
    The company upgraded their personnel
   The company upgraded their personnel
   
3. Give better travel conditions to  ( upgrade )
   give better travel conditions to
    The airline upgraded me when I arrived late and Coach Class was full
   The airline upgraded me when I arrived late and Coach Class was full
   
4. Get better travel conditions  ( upgrade )
   get better travel conditions
    I upgraded to First Class when Coach Class was overbooked
   I upgraded to First Class when Coach Class was overbooked
   
5. Give a promotion to or assign to a higher position  ( advance , kick upstairs , raise , elevate , promote , upgrade )
   give a promotion to or assign to a higher position
    John was kicked upstairs when a replacement was hired
   John was kicked upstairs when a replacement was hired
    Women tend not to advance in the major law firms
   Women tend not to advance in the major law firms
    I got promoted after many years of hard work
   I got promoted after many years of hard work
   

 extreme extreme /ɪkˈstriːm/

adjective

1. () Of the greatest possible degree, extent or intensity  ( uttermost , utmost , extreme )
   of the greatest possible degree, extent or intensity
    Extreme cold
   extreme cold
    Extreme caution
   extreme caution
    Extreme pleasure
   extreme pleasure
    Utmost contempt
   utmost contempt
    To the utmost degree
   to the utmost degree
    In the uttermost distress
   in the uttermost distress
   
2. () Far beyond a norm in quantity, amount or degree; to an utmost degree  ( extreme )
   far beyond a norm in quantity, amount or degree; to an utmost degree
    An extreme example
   an extreme example
    Extreme temperatures
   extreme temperatures
    Extreme danger
   extreme danger
   
3. () Beyond a norm in views or actions  ( extreme )
   beyond a norm in views or actions
    An extreme conservative
   an extreme conservative
    An extreme liberal
   an extreme liberal
    Extreme views on integration
   extreme views on integration
    Extreme opinions
   extreme opinions
   
4. () Most distant in any direction  ( extreme )
   most distant in any direction
    The extreme edge of town
   the extreme edge of town
   

noun

1. () The furthest or highest degree of something  ( extreme )
   the furthest or highest degree of something
    He carried it to extremes
   he carried it to extremes
   
2. () The point located farthest from the middle of something  ( extreme point , extremum , extreme )
   the point located farthest from the middle of something
    Climbing Mount Everest represents the extreme of human endurance and challenge.
   Climbing Mount Everest represents the extreme of human endurance and challenge.
   
   

 pen nib pen nib /pɛn nɪb/

noun

1. The writing point of a pen  ( nib , pen nib )
   the writing point of a pen
    The nib of my pen broke, so I need to buy a new one
   The nib of my pen broke, so I need to buy a new one